Generic Viagra Review
Generic Viagra is a medicine to increase potency and treat chronic erectile dysfunction. The main active ingredient of the drug is Sildenafil citrate.
Sildenafil citrate has been synthesized in the laboratory by a pharmaceutical company Pfizer entirely by accident. This accidental discovery of the unusual characteristics of Sildenafil has influenced on the entire pharmaceutical industry and opened new opportunities during the medication of the erectile dysfunction.
Generic Viagra is a vasodilating product which helps to achieve erection at any age. Men of middle age and senior men whose low erection is related to the physiological and biochemical changes in the body better feel the action of this drug. But even if you have a strong and healthy erection, the use of Generic Viagra will help to achieve brighter sensations during orgasm and bring more satisfaction to a sexual partner.
Generic Viagra will help to restore erection during:
- Diabetes mellitus
- Vascular diseases
- Psychological disorders: depression, anxiety and other emotional disorders.
- Administration of the strong medications: antidepressants, pain medications, and others.
An evident advantage of Generic Viagra is a high efficiency – 99,9%. Exclusions are hormonal factors of the erectile dysfunctions which are related to the decreased level of the male sexual hormone testosterone. If an erectile dysfunction became a result of the decreased level of testosterone, the use of Generic Viagra will be pointless.
Formulation and presentation of Generic Viagra
Generic Viagra is produced in the form of pills and capsules for the oral use. The pills contain:
Main active ingredient: Sildenafil Citrate.
Auxiliary ingredients: croscarmellose sodium, calcium hydrogenphosphate, magnesium stearate.
The cover of the pill may contain: lactose, triacetin, biotin, vanillin (or other food flavors for flavoring a pill)
Every pill/capsule of Generic Viagra may contain 25 mg, 50 mg, or 100 mg of the active ingredient Sildenafil citrate. As the pills and capsules should not be broken in order to keep the cover, different doses have been developed. It helps to select a more effective and safe dosage regimen in every medical case.
Viagra or Generic Viagra?
Viagra is a brand name of the active ingredient Sildenafil citrate which has been registered in 1998. Pfizer company has exclusive rights to this brand name, and none company can use this trade mark during the development of medicines on the basis of Sildenafil.
Generic Viagra is unpatented name of sildenafil that may be used by any pharmaceutical companies. This opportunity is actively used by the Indian corporations which develop drugs for the medication of the erectile dysfunction on the basis of Sildenafil citrate.
Generic Viagra contains the same active ingredient as Brand Viagra (the same amount). Their therapeutic characteristics and security index are completely identical. A different is a price: Generic Viagra 100 mg is by several times cheaper than the original brand drug.
Expenses for the creation, study, laboratory tests, advertising and promotion of brand Viagra have caused a high cost for a final customer. Generic Viagra is produced by the studies and proved chemical formula, and the expenses for the advertisement of Generic are insignificant. Therefore, a purchase of Generic Viagra 100 mg will be by 3-4 times cheaper.
Mechanism of the pharmacological action
A physiological mechanism of the erectile function is conditioned by the release of nitric oxide in the smooth muscle fibers of the cavernous bodies during the sexual stimulation. A sexual stimulation may be visual or tactile. At this moment, a signal from the brain goes through the central nervous system and nitric oxide is produced. As a result, the blood vessels are dilated in the area of the penis, and erection appears. If there is a disorder of the erectile mechanism on some of the stages, a man has erectile dysfunction.
Sildenafil citrate is a phosphodiesterase type 5 inhibitors. This enzyme regulates a production of the nitric oxide and its vasodilating characteristics.
When Sildenafil citrate is absorbed into the systemic blood flow, it temporarily blocks the work of this enzyme, and a lot of nitric oxide is synthesized in the cavernous bodies of the penis during the sexual stimulation. It leads to the dilation of the blood vessels, an improved blood circulation, and better blood filling of the cavernous bodies. When the cavernous bodies are increased, the blood outflow from the penis slows, due to which a firm and long-term erection is kept till the end of the sexual intercourse.
Main characteristics of the pharmacological properties of Sildenafil citrate
Sildenafil citrate acts selectively to PDE5 enzyme and only in the area of small pelvic. It does not provide a general vasodilating action and does not influence on the functions of the cardiovascular system
Sildenafil does not influence directly on the production of nitric oxide. It blocks the work of the enzymes which worsen the production of this enzyme during the sexual arousal
Sildenafil does not influence on the level of the sexual arousal. It does not contain the male sexual hormones (testosterone and dihydrotestosterone), and therefore it is not able to cause a strong sexual arousal and does not cure of the libido disorder
Generic Viagra (Sildenafil) is not able to block PDE5 on a recurring basis. The action of the drug lasts for about 4-5 hours, and then a concentration of Sildenafil drops in the blood plasma. At the same time, a recovery of the biological and physiological characteristics of phosphodiesterase type 5 happens, and this enzyme regulates a process of the nitric oxide release again.
Sildenafil is not able to cure of the erectile dysfunction. It does not influence on a cause of the sexual pathology and is specially developed in order to give a man an opportunity to have a complete sexual intercourse even during severe forms of the erectile dysfunction.